Article

A synthetic route to anandamide analogues carrying a substituent at the terminal carbon and an acetylene group in the end pentyl chain

Organix, Inc., 240 Salem Street, Woburn, MA 01801, USA
Tetrahedron Letters (Impact Factor: 2.4). 01/2004; 45(28):5449-5451. DOI: 10.1016/j.tetlet.2004.05.071

ABSTRACT A versatile sequence is developed for the synthesis of anandamide analogues with an acetylene group in the end pentyl chain carrying a substituent at the terminal carbon of the chain. These analogues are important for SAR studies of the endocannabinoid, anandamide.

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