Article

[Chemical constituents from roots of Machilus yaoshansis].

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 05/2012; 37(9):1227-31. pp.1227-31
Source: PubMed

ABSTRACT To study chemical constituents contained in ethanol extracts from roots of Machilus yaoshansis. Fifteen compounds were separated from the roots of M. yaoshansis by using various chromatographic techniques. Their structures were identified on the basis of their physicochemical properties and spectral data as twelve lignans(+)-guaiacin (1), kadsuralignan C (2), (+)-isolariciresinol (3), 5'-methoxy-(+)-isolariciresinol (4), (7'S, 8R, 8'R)-lyoniresinol (5), meso-secoisolariciresinol (6), isolariciresinol-9'-O-beta-D-xylopyranoside (7), 5'-methoxy-isolariciresinol-9'-O-beta-D-xylopyranoside (8), lyoniresinol-9'-O-beta-D-xylopyranoside (9), (2R, 3R) -2, 3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-5-(E)-propenylbenzofuran (10), 3, 5'-dimethoxy-4', 7-epoxy-8, 3'-neolignan-4, 9, 9'-triol (11), nectandrin B (12), and three flavanes(+)-catechin (13), (-)-epicatechin (14), and bis-8, 8'-catechinylmethane (15). All of the compounds 1-15 were separated from M. yaoshansis for the first time.

0 0
 · 
0 Bookmarks
 · 
41 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-5-(E)-propenylbenzofuran
 
5'-methoxy-(+)-isolariciresinol
 
5'-methoxy-isolariciresinol-9'-O-beta-D-xylopyranoside
 
8'R)-lyoniresinol
 
bis-8
 
compounds 1-15
 
flavanes(+)-catechin
 
isolariciresinol-9'-O-beta-D-xylopyranoside
 
kadsuralignan C
 
lignans(+)-guaiacin
 
lyoniresinol-9'-O-beta-D-xylopyranoside
 
M. yaoshansis
 
Machilus yaoshansis
 
meso-secoisolariciresinol
 
nectandrin B
 
physicochemical properties
 
spectral data
 
structures
 
study chemical constituents
 
various chromatographic techniques
 

Bo Liu