Letter: endoscopic balloon dilatation or Download full-text
strictureplasty for stricturing Crohn's
disease? Authors’ reply
A. Gustavsson*,†, B. Blomberg*, M. Andersson‡,
J. Halfvarson*,†& C. Tysk*,†
*Division of Gastroenterology, Department of Medicine, Örebro
University Hospital, Örebro, Sweden.
†School of Health and Medical Sciences, Örebro University, Örebro,
‡Department of Surgery, Örebro University Hospital, Örebro, Sweden.
SIRS, We thank Drs Yamamoto and Shiraki for their let-
ter1about our article.2We agree with their comments
on the need for prospective trials on the optimal treat-
ment of intestinal strictures in Crohn's disease. More
studies on the best medical treatment for prevention of
recurrent stricture formation after an intestinal resection
are required. Furthermore, evidence-based recommenda-
tions on the best possible treatment of a short intestinal
stricture are absent.
Neither a strictureplasty nor endoscopic dilation cures
Crohn's disease. Hence, the best symptomatic treatment
in the long-term perspective needs to be assessed while
taking into account frequency of recurrence, complica-
tions, health-related quality of life and also health-eco-
nomic aspects. We agree on the need for prospective
controlled trials comparing strictureplasty with endo-
Declaration of personal interests: Anders Gustavsson has
served as a speaker for MSD. Jonas Halfvarson has
served as a speaker for MSD, Abbott and Renapharma
Vifor. Curt Tysk has served as a speaker for Tillotts
Pharma, Falk Pharma, Ferring, MSD and AstraZeneca.
Declaration of funding interests: The study was funded in
part by The Foundation for Clinical Research in Inflam-
matory Bowel Disease, United States and Uppsala-
Örebro Regional Research Council, Sweden.
1. Yamamoto T, Shiraki M. Letter: endoscopic balloon dilatation or
strictureplasty for stricturing Crohn's disease? Aliment Pharmacol
Ther 2012; 36: 403.
2. Gustavsson A, Magnuson A, Blomberg B, Andersson M,
Halfvarson J, Tysk C. Endoscopic dilation is an efficacious and
safe treatment of intestinal strictures in Crohn's disease. Aliment
Pharmacol Ther 2012; 36: 151–8.
Aliment Pharmacol Ther 2012; 36: 403-404
ª 2012 Blackwell Publishing Ltd
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