Article

Pre-symptomatic transmission of pandemic influenza H1N1 2009: investigation of a family cluster, Brazil

Secretariat of Health Surveillance, Brazilian Ministry of Health, Brasilia, Brazil.
Epidemiology and Infection (Impact Factor: 2.49). 07/2012; 141(4):1-4. DOI: 10.1017/S0950268812001501
Source: PubMed

ABSTRACT SUMMARY We investigated the first cluster of pandemic influenza H1N1 2009 reported in Brazil in May 2009. The index case-patient had travelled from the USA and had contact with 11 relatives before she presented with symptoms. We conducted face-to-face or telephone interviews with the index case-patient and all suspect cases. We found evidence of pre-symptomatic transmission of the virus to four of her contacts. This finding has public health implications because it indicates that viral transmission in communities may not be prevented solely by isolating symptomatic case-patients.

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