Article

Validation of the Face Name Associative Memory Exam in cognitively normal older individuals.

Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.
Journal of Clinical and Experimental Neuropsychology (Impact Factor: 2.16). 07/2012; 34(6):580-7. DOI: 10.1080/13803395.2012.666230
Source: PubMed

ABSTRACT The recently developed Face Name Associative Memory Exam (FNAME), a challenging paired associative learning task, shows promise in detecting the subtle cognitive changes characteristic of preclinical Alzheimer's disease. In this study, we evaluated the validity and reliability of the FNAME in 210 cognitively normal older individuals (58-90 years of age). Construct validity of the measure was assessed by principal components analysis, which revealed two independent factors. Correlations between the FNAME subtests and another episodic memory test were significant. The results indicated strong test-retest reliability in a subsample (n = 41). Normative data stratified by age were also generated.

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    • "Using the factor weights from this prior analysis, a factor score for memory was derived for each participant. The tests included in this factor score are the following: number of errors produced on the Self-Ordered Pointing task (95% of older participants completed; adapted from Petrides and Milner, 1982; Shimamura and Jurica, 1994), cued recall names, and cued recall occupations scores from the Face-Name Associative Memory Exam (99% of older participants completed; Amariglio et al., 2012; Rentz et al., 2011), delayed recall from the Six- Trial Selective Reminding Test (99% of older participants completed; Masur et al.,1990), and Free Recall, list two, from the Memory Capacity Test (99% of older participants completed; Rentz et al., 2010). Missing data on individual tests were imputed using a linear regression approach. "
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    • "Previous work in a larger sample of older adults (n = 210) showed two underlying factors comprising the original FNAME—face–name recall (IRN, CRN, CRN30) and face–occupation recall (IRO, CRO, CRO30)—explaining 76% and 17% of the variance , respectively, in a Principal Components Analysis (Amariglio et al., 2012). Given these findings, we created equivalent summary scales for FNAME-12: FN-N items (IRN, CRN, CRN30) and FN-O items (IRO, CRO, CRO30) as well as a Total Score (FN-N + FN-O). "
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