Probable Clindamycin-Induced Ageusia, Xerostomia, and Burning Mouth Syndrome

University of California Irvine Medical CenterOrange, CA.
Annals of Pharmacotherapy (Impact Factor: 2.06). 07/2012; 46(7-8):1119-20. DOI: 10.1345/aph.1R234
Source: PubMed
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  • Annals of Pharmacotherapy 10/2012; 46(11). DOI:10.1345/aph.1R234a · 2.06 Impact Factor
  • Annals of Pharmacotherapy 10/2012; DOI:10.1345/aph.1R234b · 2.06 Impact Factor
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    ABSTRACT: Authors' contributions This work was carried out in collaboration between all authors. Author VVB wrote abstract and discussion. Author VB wrote introduction and searched the literature. Author DVJ took the photos and wrote section case report. All authors read and approved the final manuscript. ABSTRACT We report a case of a 74-year-old female patient who presented with symptoms of burning mouth. The patient suffered from hypertension and had been using the following antihypertensive drugs: Angiotensin converting enzyme inhibitor (ACE)-ramipril with felodipine (calcium channel blocker) (Triapin-2.5mg a day) during the past year and a half. After one year of Triapin intake, symptoms of burning mouth evolved. Seven days after the replacement of the offending drug with losartan (angiotensin II receptor antagonist), the burning symptoms disappeared. This case stresses the fact that in cases of patients with oral burning, the symptoms can easily vanish after the withdrawal of the offending drug.