Differential distribution of ABCB1 and ABCC1 transporters in sea urchin pluteus larvae.
ABSTRACT ABC transporters are expressed in eukaryotic and prokaryotic cell membranes, and are involved in the transport of ions and several endogenous or exogenous compounds. Intracellular calcein accumulation assays associated with ABC transporter blockers have been used to evaluate ABC proteins activity in several cell types. Here we show a notable differential distribution pattern of ABCB1 and ABCC1 transporter activity in sea urchin pluteus larvae. Mol. Reprod. Dev. © 2012 Wiley Periodicals, Inc.