Fiber Surface Modification Technology for Fiber-Optic Localized Surface Plasmon Resonance Biosensors

National Key Laboratory for Electronic Measurement Technology, North University of China, Taiyuan 030051, Shanxi, China.
Sensors (Impact Factor: 2.25). 12/2012; 12(3):2729-41. DOI: 10.3390/s120302729
Source: PubMed


Considerable studies have been performed on the development of optical fiber sensors modified by gold nanoparticles based on the localized surface plasmon resonance (LSPR) technique. The current paper presents a new approach in fiber surface modification technology for biosensors. Star-shaped gold nanoparticles obtained through the seed-mediated solution growth method were found to self-assemble on the surface of tapered optical fibers via amino- and mercapto-silane coupling agents. Transmitted power spectra of 3-aminopropyltrimethoxy silane (APTMS)-modified fiber were obtained, which can verify that the silane coupling agent surface modification method is successful. Transmission spectra are characterized in different concentrations of ethanol and gentian violet solutions to validate the sensitivity of the modified fiber. Assembly using star-shaped gold nanoparticles and amino/mercapto silane coupling agent are analyzed and compared. The transmission spectra of the gold nanoparticles show that the nanoparticles are sensitive to the dielectric properties of the surrounding medium. After the fibers are treated in t-dodecylmercaptan to obtain their transmission spectra, APTMS-modified fiber becomes less sensitive to different media, except that modified by 3-mercaptopropyltrimethoxy silane (MPTMS). Experimental results of the transmission spectra show that the surface modified by the gold nanoparticles using MPTMS is firmer compared to that obtained using APTMS.

Download full-text


Available from: Qiang Zhang, Sep 29, 2015
1 Follower
38 Reads
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: A tapered fiber localized surface plasmon resonance (LSPR) sensor is demonstrated for refractive index sensing and label-free biochemical detection. The sensing strategy relies on the interrogation of the transmission intensity change due to the evanescent field absorption of immobilized gold nanoparticles on the tapered fiber surface. The refractive index resolution based on the interrogation of transmission intensity change is calculated to be 3.2×10<sup>?5</sup> RIU. The feasibility of DNP-functionalized tapered fiber LSPR sensor in monitoring anti-DNP antibody with different concentrations spiked in buffer is examined. Results suggest that the compact sensor can perform qualitative and quantitative biochemical detection in real-time and thus has potential to be used in biomolecular sensing applications.
    Optics Express 09/2012; 20(19):21693-701. DOI:10.1364/OE.20.021693 · 3.49 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Fiber optics enable direct optical spectroscopy (from the IR to the UV; in absorption, emission and plasmonic resonance) to be performed at inaccessible sites, over large distances, in strong magnetic fields and in harsh environment. If equipped with chemically responsive coatings, they also enable species to be sensed that are not directly amenable to optical spectroscopy.
    Analytical Chemistry 11/2012; 85(2). DOI:10.1021/ac303159b · 5.64 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: An optical sensor based on the coupling between the plasmonic and photonic resonance modes in metallic photonic crystals is investigated. Large-area metallic photonic crystals consisting of periodically arranged gold nanostructures with dimensions down to sub-100 nm are fabricated using solution-processible gold nanoparticles in combination with interference lithography or interference ablation, which introduces a variety of fabrication techniques for the construction of this kind of sensor device. Sensitivity of the plasmonic response of the gold nanostructures to the changes in the environmental refractive index is enhanced through the coupling between the narrow-band photonic resonance mode and the relatively broad-band plasmon resonance, which is recognized as a Fano-like effect and is utilized to explore sensors. Theoretical modeling shows the characterization and the optimization of the sensitivity of this kind of sensor device. Theoretical and experimental results are demonstrated for the approaches to improve the sensitivity of the sensor device.
    Sensors 12/2012; 12(9):12082-97. DOI:10.3390/s120912082 · 2.25 Impact Factor
Show more