Complete Genome Sequence of an H7N3 Avian Influenza Virus Isolated from Ducks in Southern China

MOA Key Laboratory for Animal Vaccine Development, Key Laboratory of Zoonoses Control and Prevention of Guangdong, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Journal of Virology (Impact Factor: 4.44). 07/2012; 86(14):7724-5. DOI: 10.1128/JVI.01063-12
Source: PubMed


We report here the complete genomic sequence of an H7N3 avian influenza virus (AIV) isolate, which was obtained from duck in 1996. This is the first report of this subtype of AIV being isolated from duck in Guangdong of Southern China. Genomic sequence and phylogenetic analyses showed that it was highly homologous with the wild bird virus A/ruddy turnstone/Delaware Bay/135/1996 (H7N3) and that all eight genes of this virus belonged to the North America gene pool. The availability of genome sequences is helpful to further investigations of epidemiology and evolution of AIV between waterfowl and wild birds.

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Available from: Peirong Jiao, May 10, 2014
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    • "However, only one strain, H9N2 virus, was isolated from humans in Hong Kong in 2008 and there have been no H7 subtype AIVs isolated in Hong Kong in recent years. In Southern China, H5N1 AIV was isolated from a condor in Guangdong in 200324; H5N2 and H5N1 AIV were isolated from parrots in Guangdong in 2004 and 20052526, respectively; several H9N2 AIVs were isolated from water and fowl feces in the Dongting Lake wetland in 200727, and from broilers in Fujian in 200928; 4 H7N3AIVs were isolated from domestic ducks in Zhejiang in 201129; H6N2 AIV was isolated from a chicken in Guangdong in 201130; recombinant H9N2 AIV from fresh egret feces in the wetland in 201231; and H10N8 AIVs were isolated from water samples of the wetland in 201132, and from a duck in Guangdong in 201233. Prior reports showed that from January 2000 through April 2001, multiple H3N6, H9N2, H2N9, H3N3, and H4N6 AIVs and single H1N1 and H3N2 AIVs were isolated from a Nanchang live poultry market34. "
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    ABSTRACT: Extensive surveillance of influenza A viruses in different avian species is critical for understanding its transmission. Here, a breeding colony of Little Egrets and Black-crowned Night Herons was monitored both serologically and virologically in a city park of Jiangxi in 2009. A portion of herons had antibodies against H7 (52%), H5 (55%) and H9 (6%) subtype avian influenza virus (AIV) in egg yolk samples, and 45% had antibodies against different AIV serotypes (H5, H7 or H9) simultaneously. Greater numbers of samples with anti-AIV H5N1 recombination-4 (Re-4, clade 7) antibodies were measured compared with those containing anti-H5N1 Re-1 (clade 0) and Re-5 (clade 2.3.4) antibodies. Eight strains of H5 and 9 strains of H9 were isolated from poultry of nearby markets. These results indicate wild birds are at risk from infection and co-infection with H7, H5, and H9 subtypes. Investigation of wild bird infection might provide an early warning sign of potential novel AIVs circulating in the nearby poultry industry and even in human society.
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