The lymphoid system. Its normal architecture and the potential for its understanding by the study of lymphoproliferative diseases

Human Pathlogy (Impact Factor: 2.77). 02/1978; 9(1):25-45. DOI: 10.1016/S0046-8177(78)80005-7
Source: PubMed


This article presents a view of lymphoid tissue architecture as defined by the traffic of defined lymphoid cell classes. The compartmentalization of lymphocytes is discussed in reference to specific cell-cell interactions that occur in antigen-driven immune responses. Finally, the distribution of normal and neoplastic lymphocytes in humans is defined and compared with animal model systems.

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