Article
Rotavirus genotypes in Slovenia: Unexpected detection of G8P[8] and G12P[8] genotypes
Journal of Medical Virology (impact factor:
2.82).
04/2007;
79(5):626 - 632.
DOI:10.1002/jmv.20811
pp.626 - 632
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Citations (0)
- Cited In (3)
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Article: Serotype g12 rotaviruses, Lilongwe, Malawi.
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ABSTRACT: To assess diversity of rotavirus strains in Lilongwe, Malawi, we conducted a cross-sectional study of children with acute gastroenteritis, July 2005-June 2007. Serotype G12 was identified in 30 (5%) of 546 rotavirus-positive fecal specimens. The G12 strain possessed multiple electropherotypes and P-types, but their viral protein 7 sequences were closely related, indicating that reassortment has occurred.Emerging Infectious Diseases 02/2009; 15(1):87-90. · 6.79 Impact Factor -
Article: Molecular epidemiology of rotaviruses in Bulgaria: annual shift of the predominant genotype.
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ABSTRACT: Rotavirus molecular epidemiology investigations provide important information about the incidence of rotavirus diseases and rotavirus strains in circulation in the prevaccine era. The purpose of this investigation was to study the burden of rotavirus disease, rotavirus strain diversity, and epidemiology specificities of rotavirus infections in Bulgaria. A total of 3,130 stools collected between 2005 and 2008 were tested by immune enzyme tests. G-P genotype identification of rotavirus strains were performed by reverse transcriptase polymerase chain reaction (RT-PCR). Rotavirus etiology was confirmed in 32.4% of the samples tested. Rotaviruses affected predominantly children under 5 years of age (95.5%), with a peak prevalence between the ages of 7 and 36 months. Four of the five globally distributed rotavirus strains (G1P[8], G2P[4], G4P[8], and G9P[8]) constituted 97.7% of all rotavirus strains in circulation. However, annual shifts of predominant rotavirus G-P genotypes were observed from season to season-G4P[8] was predominant in rotavirus season 2004/2005 (56.8%), but was replaced by G9P[8] in 2005/2006 (77.7%), and G2P[4] (41.6%) and G1P[8] (39.5%) in the following two consecutive rotavirus seasons. Year-round circulation of rotaviruses in the country with increased incidence in the winter-spring season and unexpected peaks preceding the rotavirus seasons were observed. Molecular epidemiology data are needed in Bulgaria for health policy makers in order to introduce routine rotavirus vaccination. The monitoring of rotavirus genetic diversity in Bulgaria in the postvaccination period will contribute to a successful rotavirus vaccination program.European Journal of Clinical Microbiology 03/2010; 29(5):555-62. · 2.86 Impact Factor -
Article: Identification of lineage III of G12 rotavirus strains in diarrheic children in the Northern Region of Brazil between 2008 and 2010.
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ABSTRACT: This study reports on the surveillance for rotavirus genotypes and the identification of G12 human rotavirus in the Northern Region of Brazil. Rotavirus-positive samples were collected from children <5 years of age with acute diarrhea from January 2008 to October 2010. G2P[4] was the most prevalent genotype, accounting for 45.6% (126/303) of cases. Five rotavirus strains bearing G12P[6] genotype specificity were detected. Phylogenetic analysis of the VP7 gene showed that G12 strains clustered into lineage III. This is the first detection of G12 strains from lineage III in Latin America, broadening the current evidence for the worldwide emergence of this genotype.Archives of Virology 09/2011; 157(1):135-9. · 2.11 Impact Factor
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Keywords
10 samples
2 samples
26 samples
72 samples
acute viral gastroenteritis
animal-human genome reassortment
confirmed rotavirus-positive samples
G1 genotype
genotype G
interspecies transmission
J. Med
molecular characterization
NSP4 genotype B
P[8] genotype specificity
P[8] lineage II
rotavirus G
rotavirus G12 detection
sequence analysis
Stool samples
VP7-based phylogenetic analysis
