Candidate genes for growth traits in beef cattle crosses Bos taurus × Bos indicus

Journal of Animal Breeding and Genetics (Impact Factor: 1.57). 01/2003; 120(1):51 - 56. DOI: 10.1046/j.1439-0388.2003.00371.x


Candidate gene strategy has been proposed to direct the search for quantitative trait loci, and polymorphisms at these loci have been associated with several production traits in bovine. A total of 211 animals resulting from crosses between Nelore females with sires from either Aberdeen Angus, Canchim and Simmental breeds were analyzed for restriction fragment length polymorphisms (RFLPs) in the κ-casein, β-lactoglobulin (LGB) and growth hormone GH genes. Average daily gain from birth to weaning (GBW) and from weaning to yearling (GWY) were analyzed by a statistical model comprising RFLP genotypes and their interaction effects. Significant effects (p < 0.05) of growth hormone (GH) and of the interaction β-lactoglobulin × GH were verified for the GWY. Animals with LL genotypes for GH had higher GBW than LV animals but lower GWY (p < 0.05).
Für die direkte Suche nach QTLs ist der Kandidatengen-Ansatz eine Möglichkeit und Polymorphismen in diesen Genen zeigen Assoziationen zu Produktionsmerkmalen beim Rind auf. Insgesamt wurden 211 Tiere aus Kreuzungen zwischen Nelore-Kühen und Aberdeen Angus-, Canchim- oder Simmental-Bullen für die Analyse von RFLPs im κ-Kasein, β-Laktoglobulin (LGB) und Wachstumshormon (GH) verwendet. Die durchschnittliche tägliche Zunahme von der Geburt bis zum Absetzen (GBW) und vom Absetzen bis zum Alter von einem Jahr (GWY) wurden durch ein statistisches Modell unter Berücksichtigung der RFLP-Genotypen und deren Interaktionen analysiert. Signifikante Effekte (p < 0,05) von GH und die Interaktion β-LGB × GH wurden für GWY verifiziert. Tiere mit dem Genotyp GH × LL hatten höhere GBWs als LV-Tiere, jedoch niedrigere GWY (p < 0,05).

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