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Visceral leishmaniasis mimicking autoimmune hepatitis, primary biliary cirrhosis, and systemic lupus erythematosus overlap.

Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital Besevler, 06500 Ankara, Turkey.
The Korean Journal of Parasitology (Impact Factor: 0.88). 06/2012; 50(2):133-6. DOI: 10.3347/kjp.2012.50.2.133
Source: PubMed

ABSTRACT Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.

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