Article

Method for Determining the Characteristics of an Epithermal-Neutron Beam for Boron-Neutron-Capture Therapy

TRINITI
Atomic Energy (impact factor: 0.08). 12/2003; 96(1):52-56. DOI:10.1023/B:ATEN.0000022814.22066.cb pp.52-56

ABSTRACT Epithermal neutrons are used in boron-neutron-capture therapy to remove multiform glioblastomas and deep-lying melanoma tumors. Thermal neutrons interact with 10B which is preintroduced as a pharmacological preparation. The reaction products kill malignant tumor cells.A beam of epithermal neutrons from a nuclear reactor is formed using collimators and specially assembled additional moderators. A method where detectors with 235U, screened by 10B with different thickness and placed in a vertical array perpendicular to the beam, is proposed for obtaining real-time information. The neutron flux near E

i
and the spectrum in a wide range are determined from the difference of the signals from before and after detectors.

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Keywords

additional moderators
 
deep-lying melanoma tumors
 
different thickness
 
malignant tumor cells.A beam
 
multiform glioblastomas
 
nuclear reactor
 
pharmacological preparation
 
reaction products
 
signals
 
vertical array perpendicular
 

Yu. A. Kashchuk