Chapter

Bipolar Disorder: A Neurobiological Synthesis

10/2010; DOI:10.1007/7854_2010_98 pp.331-340

ABSTRACT Bipolar disorder (BPD) is a common, chronic, recurrent mental illness affecting 1–2% of the general population (Goodwin and
Jamison 2007). Clinically, it is one of the most debilitating medical illnesses, and a growing number of recent studies indicate that
outcome is quite poor for many individuals with BPD. Afflicted patients generally experience high rates of relapse, a chronic
recurrent course, lingering residual symptoms, cognitive and functional impairment, psychosocial disability, and diminished
well-being. Furthermore, the disorder is frequently unrecognized, misdiagnosed, and mismanaged, and much still remains unknown
about its pathophysiology.

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Keywords

Bipolar disorder
 
chronic
 
debilitating medical illnesses
 
misdiagnosed
 
mismanaged
 
pathophysiology
 
recent studies
 
recurrent mental illness
 
relapse
 
residual symptoms