Computer Analysis of 2-D Images

DOI: 10.1385/1-59259-890-0:267 In book: The Proteomics Protocols Handbook, pp.267-277


Indeed, the development of two-dimensional (2-D) electrophoresis technology has provided an important research tool for comparative
proteomics. A number of other technologies for protein separation have also been investigated in the last few years, such
as protein chips, liquid chromatography, and high-pressure liquid chromatography, to name just a few. However, 2-D gels are
still considered the workhorse among research laboratories willing to accurately track changes in protein expression and to
achieve differential proteomics.

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