Host range expansion of honey bee Black Queen Cell Virus in the bumble bee, Bombus huntii
ABSTRACT Here we provide the first evidence that Black Queen Cell Virus (BQCV), one of the most prevalent honey bee viruses, can cause
an infection in bumble bees, Bombus huntii, and that the BQCV infection could spread to different tissues of bumble bees. The detection of negative strand RNA of BQCV,
an indicator of active virus replication, in the gut of B. huntii suggests that virus particles replicate within the gut and then cross the gut lining to other tissues through hemolymph circulation.
The observation of active replication of the BQCV in the gut, together with the fact that BQCV was more widespread in the
body of field-collected bees than that of lab-reared bees, implies a possible association between the foraging activities
of bumble bees and virus transmission. The fact that bumble bees and honey bees are able to share nectar and pollen resources
in the same field suggests that geographical proximity of two host species could play a role in host range breadth of BQCV.
Keywordshost range–bumble bee–
–Black queen cell virus
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ABSTRACT: We present the case of a patient from South America with a lung disease that was initially diagnosed as sarcoidosis and treated with corticoids. Despite an initial improvement, the patient worsened gradually until his condition was finally attributed to paracoccidioidomycosis. This systemic mycosis has features in common with sarcoidosis, but the treatment differs drastically because corticoids can place the patient's life at risk.Radiología 04/2011; 53(6):560-3.
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ABSTRACT: Pathogens and parasites represent significant threats to the health and well-being of honeybee species that are key pollinators of agricultural crops and flowers worldwide. We conducted a nationwide survey to determine the occurrence and prevalence of pathogens and parasites in Asian honeybees, Apis cerana, in China. Our study provides evidence of infections of A. cerana by pathogenic Deformed wing virus (DWV), Black queen cell virus (BQCV), Nosema ceranae, and C. bombi species that have been linked to population declines of European honeybees, A. mellifera, and bumble bees. However, the prevalence of DWV, a virus that causes widespread infection in A. mellifera, was low, arguably a result of the greater ability of A. cerana to resist the ectoprasitic mite Varroa destructor, an efficient vector of DWV. Analyses of microbial communities from the A. cerana digestive tract showed that Nosema infection could have detrimental effects on the gut microbiota. Workers infected by N. ceranae tended to have lower bacterial quantities, with these differences being significant for the Bifidobacterium and Pasteurellaceae bacteria groups. The results of this nationwide screen show that parasites and pathogens that have caused serious problems in European honeybees can be found in native honeybee species kept in Asia. Environmental changes due to new agricultural practices and globalization may facilitate the spread of pathogens into new geographic areas. The foraging behavior of pollinators that are in close geographic proximity likely have played an important role in spreading of parasites and pathogens over to new hosts. Phylogenetic analyses provide insights into the movement and population structure of these parasites, suggesting a bidirectional flow of parasites among pollinators. The presence of these parasites and pathogens may have considerable implications for an observed population decline of Asian honeybees.PLoS ONE 01/2012; 7(11):e47955. · 3.53 Impact Factor