Genetics and the human lineage
ABSTRACT Genetics has greatly contributed to current knowledge about the evolution of the human lineage. Immunological techniques and
the molecular clock have addressed the time divergence of human and chimpanzee lineages, disproving the late divergence model.
The much-debated question about the origin of anatomically modern humans has been greatly by investigations of mitochondrial
DNA, Y-chromosome DNA, and other genetic polymorphisms, all of which have also shed light on the size of human populations
through hominid history. The persistent controversy concerning the relationship between Neanderthal and modern human populations
has recently been constrained by the analysis of mitochondrial DNA fossil Neanderthals and early modern humans. Finally, recent
genetic discoveries have contributed to unravelling the phylogenetic history of distinctive human traits, such as language
and the masticatory apparatus
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ABSTRACT: THE proteins of human serum subjected to two-dimensional zone electrophoresis, a combination of filter-paper and starch-gel electrophoresis, can be resolved into at least 21 distinct components1,2. Some of these proteins, for example, haptoglobin and transferrin, were found to be made up of components which exhibit genetically controlled variations in the human population1-3. To enlarge our view of the evolutionary process underlying such variability in serum specificities, we began a comparative study of the distribution of protein components in the sera of the Primates. So far, sera from 13 chimpanzees, 19 cynomolgus monkeys, 17 rhesus monkeys, and several other macaques in addition to human sera have been analysed by two-dimensional zone electrophoresis in a discontinuous system of buffers4,5. This communication reports on the results gathered up to now which enable us to distinguish the four primate groups and which emphasize a taxonomic gradation in the differences among the sera examined.Nature 11/1960; 188:78-9. · 38.60 Impact Factor
- Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 05/1996; 41(5):727-32.
- Science. 01/1995;