Étude préliminaire de Marrubium deserti de Noé, une Lamiaceae endémique algérienne

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Phytotherapie 01/2010; 8(6):353-358. DOI: 10.1007/s10298-010-0589-y

ABSTRACT Connue pour ses propriétés médicinales, aromatiques ou culinaires, la famille des Lamiacées présente un intérêt économique
majeur, notamment comme source d’huiles essentielles. Dans le cadre de l’étude de la biodiversité de la flore algérienne,
l’analyse phytochimique et la recherche des activités biologiques des parties aériennes de Marrubium deserti de Noé ont été entreprises. L’extraction par des solvants de polarité croissante tels que le dichlorométhane, l’acétate d’éthyle
et le butanol, puis la purification des extraits obtenus ont permis d’isoler et d’identifier à ce jour un diterpène original
de type labdane, un flavonoïde et des phénylpropanoïdes glycosylés. Les extraits et les composés isolés ont fait l’objet d’une
étude biologique comme antioxydants, antibactériens et antigénotoxiques.

Known for its medicinal, aromatic or culinary properties, the Lamiaceae family represents a major economic interest, in particular
as a source of essential oils. The purpose of this research concerns the phytochemical and the biological study of one of
the Algerian flora’s medicinal plants known as Marrubium deserti de Noé. The extraction by solvents of increasing polarity: dichloromethane, ethyl acetate and butanol led to the isolation
and identification of a novel labdane-type diterpene, a flavonoid and phenylpropanoid glycosides. Extracts and pure compounds
were tested as antioxidant, antibacterial as well as antigenotoxic.

Mots clés
Marrubium deserti
Marrubium deserti

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    ABSTRACT: AIM OF THE STUDY: The main aim of this study was to identify, catalogue and document the large number of wild medicinal plants used in the M'Sila region (northern Algeria) for the treatment of several human pathologies. Another more ambitious aim is to contribute to overcoming the limits of an orally transmitted pharmacopoeia, attempting to exploit the large ethnopharmacology patrimony of the region for further pharmacological purposes. MATERIALS AND METHODS: Our field study was carried out over a period of three years (2008-2010). During this period, herbalists were interviewed using semi-structured questionnaires investigating the herbalist as a holder of information (gender, age and educational level) and about wild medicinal plants (local name, uses and part used). In addition, the relative importance value of the species was determined and informant consensus factor (ICF) was calculated for the medicinal plants included in the study. RESULTS: A total of 83 herbalists were interviewed, men dominate the practice of traditional medicine in the region. About 41% of them are between 31-40 years, and about a third (34%) is illiterate. The traditional herbal knowledge is passed from generation to generation in the verbal form, being almost totally absent a writing tradition. The interviewed herbalists identified and recorded 58 plants species and 50 genera belonging to 27 plant families. Lamiaceae and Asteraceae were the most represented plant families. The aerial parts were the most commonly used plant part, while infusion and decoction were the most common method of traditional drug preparation. CONCLUSIONS: The survey provides a veritable source of information on the herbalists and wild medicinal plants. Plants which are used in different parts of the world for the treatment of similar diseases may be deemed to be effective in pharmacological terms. These medicinal plants may be incorporated into the healthcare delivery system of the country.
    Journal of ethnopharmacology 04/2013; · 2.32 Impact Factor


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