Article

Paraquat poisoning: Experience of Poison Control Centers in France.

Veterinary and human toxicology 02/1979; 21 Suppl:112-3. pp.112-3
Source: PubMed

ABSTRACT Seventy acute intoxications with paraquat have been collected in 11 out of the 17 French Poison Control Centers from 1970 to 1977. The main route of intoxication is oral ingestion and accounts for all the lethal cases (24). Accidental ingestion may be severe : 7 deaths out of 25 cases but suicidal intoxications have a more important morality rate : 17 deaths out of 22 cases. The addition of an emetic to the formulation of this herbicide will lower the severity of this acute poisoning and will be demonstrated by the survey of the next cases of paraquat poisoning.

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    Article: Paraquat poisoning: findings on chest radiography and CT in 42 patients.
    J G Im, K S Lee, M C Han, S J Kim, I O Kim
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    ABSTRACT: The purpose of this study is to describe the radiologic manifestations of paraquat-induced pulmonary damage, with special emphasis on the sequential changes seen with this condition. Paraquat is a herbicide that has toxic effects on the lungs, liver, and kidneys. Progressive respiratory failure is a frequent cause of death. We analyzed retrospectively 42 patients with a history of paraquat ingestion and abnormal findings on chest radiographs. Radiographic changes during the first week after ingestion included diffuse consolidation (26/39), pneumomediastinum with or without pneumothorax (15/39), and cardiomegaly with widening of the superior mediastinum (8/39). Small cystic and linear shadows began to appear at the end of the first week and were the preponderant parenchymal abnormality after 2-4 weeks. Focal honeycombing was the major parenchymal abnormality after 4 weeks. High-resolution CT of the lung 9 months after paraquat exposure revealed localized fibrosis containing small cysts. Our study shows that the pulmonary manifestations of paraquat poisoning begin with air-space consolidation, which then leads to end-stage lung.
    American Journal of Roentgenology 11/1991; 157(4):697-701. · 2.78 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

17 deaths
 
17 French Poison Control Centers
 
7 deaths
 
Accidental ingestion
 
acute poisoning
 
emetic
 
main route
 
morality rate
 
next cases
 
paraquat poisoning
 
severity