Should Recurrent Calcium Oxalate Stone formers become Vegetarians?
British Journal of Urology 01/1980; 51(6):427-31. DOI: 10.1111/j.1464-410X.1979.tb03570.x
The hypothesis that the incidence of calcium stone disease is related to the consumption of animal protein has been examined. Within the male population, recurrent idiopathic stone formers consumed more animal protein than did normal subjects. Single stone formers had animal protein intakes intermediate between those of normal men and those of recurrent stone formers. A high animal protein intake caused a significant increase in the urinary excretion of calcium, oxalate and uric acid, 3 of the 6 main urinary risk factors for calcium stone formation. The overall relative probability of forming stones, calculated from the combination of the 6 main urinary risk factors, was markedly increased by a high animal protein diet. Conversely, a low animal protein intake, such as taken by vegetarians, was associated with a low excretion of calcium, oxalate and uric acid and a low relative probability of forming stones.
Article: Medical management[Show abstract] [Hide abstract]
ABSTRACT: Kidney stones are the result of a complex interaction of hereditary and environmental factors. They are an increasingly common affliction of industrialized societies. In nearly all cases, kidney stone formation can be drastically reduced or prevented if the patient adheres closely to a carefully designed prevention program. We emphasize an approach oriented around stone composition and targeted at specific risk factors. Our approach begins with fluid and dietary modifications and progresses to pharmacological treatment in nonresponders.Clinical Reviews in Bone and Mineral Metabolism 01/2004; 2(3):237-251. DOI:10.1385/BMM:2:3:237
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ABSTRACT: El no disponer de valores normales de la densidad vertebral (DOV) por TCc en nuestra área geográfica ha hecho plantearse la posibilidad de obtener tablas propias pues es bien conocida la influencia de los factores genéticos, étnicos, nutricionales y otros en la mineralización ósea. Por otro lado, la presencia de una mayor osteopenia en un grupo de pacientes menopáusicas, con hiperpatiroidismo primario, osteodistrofia renal, nefrolitiasis cálcica y en tratamiento esteroideo crónico, hizo que se estudiara la DOV y algunos parámetros bioquímicos relacionados con el metabolismo óseo, con el fin de identificar a aquellos pacientes de riesgo. El análisis de los resultados muestra algunas diferencias entre nuestros valores de pacientes normales y la de los americanos sobre sobre todo en el grupo de mujeres. La determinación de la densidad ósea vertebral es importante sobre todo aquellas pacientes con menopausia quirúrgica, siendo las determinaciones de desoxipiridolina de parámetro que mejor predecía la DOV en las menopausias fisiológicas y el calcitriol en las menopausias quirúrgicas.
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ABSTRACT: 389 consecutive renal stone formers (275 males, 114 females) were investigated in an out-patient stone clinic. Renal tubular acidosis (RTA) was found in 83 patients (22%). Proximal RTA was twice as common as the distal tubular type. The acidification defects were exclusively of the incomplete form with normal basal blood acid-base status. Main diagnoses besides RTA were primary hyperparathyroidism (3.5%), medullary sponge kidney (3.5%), infection induced stones (3%), urate stones (2%), intestinal disorder (1.5%) and cystinuria (0.5%).The metabolic evaluation was mainly based on 24 h urine sampling on a free diet. In 248 patients (64%) no distinct abnormality was considered to be primarily responsible for stone formation. Clinical and biochemical analysis of these so-called idiopathic stone formers disclosed a male preponderance (80%) and, compared to a non-stone-forming control group, a higher urinary calcium excretion, yet with a considerable overlap between the two groups. Hyperuricosuria and hyperoxaluria were rare findings.The conclusion of the study is given as a proposal for clinical classification and ambulatory investigation of renal stone formers.Journal of Molecular Medicine 12/1982; 61(2):85-90. DOI:10.1007/BF01496659 · 5.11 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.