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Étude de l’activité antimicrobienne de l’huile essentielle d’une plante sauvage Prangos asperula Boiss

Phytotherapie 07/2007; 5(3):129-134. DOI: 10.1007/s10298-007-0238-2

ABSTRACT Prangos asperula (Pa) pousse à l’état sauvage sur les pentes des montagnes entre 1200 et 1500 mètres d’altitude au Liban et en Syrie. Plusieurs
échantillons ont été collectés de trois régions libanaises. L’extraction des huiles a été effectuée par hydrodistillation.
Nos résultats ont montré des propriétés antibactériennes de l’huile essentielle de Pa plus significatives que celles des antibiotiques communs utilisés à titre comparatif dans nos tests. L’huile essentielle
extraite de la plante a été testée contre les bactéries suivantes: Staphylococcus aureus, Streptococcus fecalis, Escherichia coli, Salmonella typhi; et contre la levure: Candida albicans. Nos résultats ont également montré un effet inhibiteur très important contre Staphylococcus aureus (de 98 à 100 %), Streptococcus fecalis (de 94 à 100 %), Escherichia coli (de 92 à 100 %), Salmonella typhi (de 91 à 100 %) et Candida albicans (100 %). Cette propriété antibactérienne contre certains gram (+) positifs et gram (−) négatifs et contre la levure Candida albicans offrent de grandes possibilités d’application dans le domaine médical.

Prangos asperula (Pa) grows wild in vast areas of Lebanon and Syria at altitudes between 1200 and 1500 m. Samples of Pa were collected from three regions of Lebanon. The extraction of oil was performed using hydrodistillation. Our results demonstrated
that Pa oil has much stronger antibacterial properties than the common antibiotics used in comparative tests. The essential oil extracted
from the plant was tested against bacteria (Staphylococcus aureus, Streptococcus faecalis, Escherichia coli and Salmonella typhi), and yeast Candida albicans). Our results showed a strong inhibitory effect against S. aureus (98 to 100%), S. faecalis (94 to 100%), E. coli (92 to 100%), S. typhi (91 to 100%) and C. albicans (100%). Its remarkable activity against some gram-positive and gram-negative bacteria demonstrates enormous potential for
medicinal use.

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