Article

Abnormal-pursuit eye movements in schizophrenia. Evidence for a genetic indicator.

Archives of General Psychiatry (Impact Factor: 13.75). 08/1977; 34(7):802-5.
Source: PubMed

ABSTRACT Disordered smooth-pursuit eye movements occur in a high percentage of schizophrenic patients and their first-degree relatives. A Test of the hypothesis that these disorders represent a genetic indicator of schizophrenia was undertaken by testing pursuit eye movements in a sample of monozygotic and dizygotic twins discordant for clinical schizophrenia. Deviant eye tracking is significantly concordant within monozygotic twin pairs, and less so with dizygotic twin pairs discordant for schizophrenia. A genetic interpretation is consistent with these results.

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