Synthesis and Crystal Structure of 1,2,3-Tri-O-acetyl-4,6-di-O-benzylidene-β-d-glucopyranose
ABSTRACT AbstractThe crystal of 1,2,3-Tri-O-acetyl-4,6-di-O-benzylidene-β-d-glucopyranose (I) was studied by X-ray diffraction. (I) crystallizes in the monoclinic space group P2
with cell parameters of a=5.691(3) Å, b=7.770(2) Å, c=22.503(7) Å, b=93.58(5)°, V=993.1(7) Å3 and Z=2. The molecular structure of (I) consists of a 4,6-O-benzylidene-glucopyranose moiety which has the 4-OH and 6-OH groups of the glucopyranose protected by glycosidic bonding to
a benzylic carbon, forming a benzyl acetal. The other OH groups of the glucopyranose ring are also protected with three acetate
groups. In the crystal structure adjacent molecules are linked by C–H···O hydrogen bonds.
Graphical AbstractSummary sentence: Acetate and benzylidene protecting groups has been employed in the synthesis of 1,2,3-Tri-O-acetyl-4,6-di-O-benzylidene-β-d-glucopyranose (I) and its crystal structure has been determined from single crystal X-ray diffraction data.