Article

A rapid method for determining phenolic endocrine disrupters in water samples

Chromatographia (Impact Factor: 1.37). 10/2002; 56(9):573-576. DOI: 10.1007/BF02497672

ABSTRACT We have developed a method based on solid-phase extraction coupled on-line to liquid chromatography with UV detection (SPE-HPLC-UV)
to determine bisphenol A and a group of alkylphenols, which have been recognized as endocrine disrupters (ED), in water samples.
We optimized the conditions used for both SPE and the chromatography. The SPE-HPLC-UV method developed is rapid and it enables
routine analysis. Its performance was checked with a variety of aqueous samples collected in the south of Catalonia from the
Ebro river, from the sea, and from tapwater-and waste-water-treatment plants. Drinking water in plastic bottles was also analyzed.
The method enabled determination of ED at low levels; the limits of detection were between 0.01 and 0.1 μg L−1. Bisphenol A and nonylphenol were dttected in some samples.

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    • "Most of them couple a pre-concentration technique, namely liquid–liquid extraction (LLE) and solid phase extraction (SPE) with gas chromatography (GC), with several types of detectors: flame ionisation detector (FID) (Almeida et al., 1996; US EPA Method 8041, 1996; European Standard, 1998; Barták et al., 2000) and electronic capture detector (ECD) (European Standard, 1998; Barták et al., 2000). There are also a significant number of publications about the determination of phenolic compounds by capillary electrophoresis (Morales and Cela, 1999; Jáuregyu et al., 2000; Morales and Cela, 2000) and by high-performance liquid chromatography (HPLC) (Zhao and Lee, 2001; Liu et al., 2003), using solid-phase extraction (SPE) (Rodrí guez et al., 2000; Brossa et al., 2002; Wissiak and Rosenberg, 2002) or solid-phase microextraction (SPME) (Gonzalez-Toledo et al., 2001; Peñ alver et al., 2002; Sarrion et al., 2002; Canosa et al., 2005), as a pre-concentration step. Some of these methods include a derivatization step, in order to improve the detection signal and the resolution between peaks, especially between isomers (Buchholz and Pawliszyn, 1994; Moeder et al., 2000; Llompart et al., 2002; Korenman et al., 2003). "
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