A rapid method for determining phenolic endocrine disrupters in water samples

Chromatographia (Impact Factor: 1.44). 10/2002; 56(9):573-576. DOI: 10.1007/BF02497672

ABSTRACT We have developed a method based on solid-phase extraction coupled on-line to liquid chromatography with UV detection (SPE-HPLC-UV)
to determine bisphenol A and a group of alkylphenols, which have been recognized as endocrine disrupters (ED), in water samples.
We optimized the conditions used for both SPE and the chromatography. The SPE-HPLC-UV method developed is rapid and it enables
routine analysis. Its performance was checked with a variety of aqueous samples collected in the south of Catalonia from the
Ebro river, from the sea, and from tapwater-and waste-water-treatment plants. Drinking water in plastic bottles was also analyzed.
The method enabled determination of ED at low levels; the limits of detection were between 0.01 and 0.1 μg L−1. Bisphenol A and nonylphenol were dttected in some samples.

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