Article

Separation and determination of ephedrine enantiomers by capillary electrophoresis usingl-leucine as chiral selector

Chromatographia (impact factor: 1.2). 10/2002; 56(9):637-639. DOI:10.1007/BF02497682 pp.637-639

ABSTRACT The separation and determination of ephedrine enantiomers by capillary electrophoresis usingl-leucine as chiral selector is described. The influence of buffer pH, buffer concentration, chiral selector concentration
and organic modifier added to the background electrolyte on the resolution of enantiomers were studied. Based on these parameters
the analytical method developed was found to be suitable for the analysis of ephedrine and related compounds inEphedra plant extracts.

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Keywords

analytical method
 
background electrolyte
 
buffer concentration
 
buffer pH
 
capillary electrophoresis usingl-leucine
 
chiral selector
 
chiral selector concentration
 
compounds inEphedra plant
 

Nengsheng Ye