Article

Concomitant pituitary adenoma and Rathke's cleft cyst

Neuroradiology (impact factor: 2.82). 08/2001; 43(9):755-759. DOI:10.1007/s002340100559 pp.755-759

ABSTRACT We reviewed the clinical, radiological and surgical findings in patients with both pituitary adenoma and Rathke's cleft cyst.
We retrospectively selected patients with both lesions from the 374 patients in whom a sellar/juxtasellar lesion was detected
on MRI at 1.5 tesla. All patients received intravenous contrast medium. Concomitant pituitary adenoma and Rathke's cleft cyst
were found in eight patients (2.1 %). The frequency of the combination was 3.5 % of pituitary adenomas and 11 % of Rathke's
cleft cysts. Symptoms were always due to the adenoma, secreting adrenocorticotrophin in two patients and growth hormone in
six. The adenoma was larger in five patients, and the cyst in three. The cysts gave variable signal. The adenoma was adjacent
to the cyst in seven patients, and enclosed it in the other patient. As a result of experience with MRI, concomitant pituitary
adenoma and Rathke's cleft cyst are now known not to be as rare as thought previously. When a nonenhancing cyst-like structure
is demonstrated in a patient with pituitary adenoma, the possibility of a coexisting Rathke's cleft cyst should be considered.

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    Article: Collision sellar lesions: experience with eight cases and review of the literature.
    Maria Koutourousiou, George Kontogeorgos, Pieter Wesseling, Andre J Grotenhuis, Andreas Seretis
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Keywords

adenoma
 
coexisting Rathke's cleft cyst
 
Concomitant pituitary adenoma
 
cysts
 
enclosed
 
growth hormone
 
intravenous contrast medium
 
lesions
 
MRI
 
nonenhancing cyst-like structure
 
patients
 
pituitary adenoma
 
pituitary adenomas
 
rare
 
Rathke's cleft cyst
 
secreting adrenocorticotrophin
 
sellar/juxtasellar lesion
 
surgical findings
 
Symptoms
 
variable signal