Laboratory model of bursting pressures of femtosecond laser-assisted penetrating keratoplasty wounds using novel pattern designs
Department of Ophthalmology, University of California, San Francisco, 10 Koret Way, K-304, San Francisco, CA 94143-0730, USAThe British journal of ophthalmology (Impact Factor: 2.98). 06/2012; 96(9):1273-4. DOI: 10.1136/bjophthalmol-2012-302037
- The British journal of ophthalmology 12/2012; 97(3). DOI:10.1136/bjophthalmol-2012-302606 · 2.98 Impact Factor
- International ophthalmology clinics 10/2013; 53(4):23-32. DOI:10.1097/IIO.0b013e3182a12b3b
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ABSTRACT: The aim of this study was to compare the outcomes of "mushroom" femtosecond laser-enabled keratoplasty (M-FLEK) with those of conventional penetrating keratoplasty (PKP) in eyes with keratoconus. The femtosecond laser-enabled "mushroom" pattern keratoplasty technique results in less postoperative astigmatism and higher endothelial cell counts compared with conventional PKP in patients with keratoconus. This was a nonrandomized retrospective, single private center clinical study. Between March 2010 and April 2012, 26 eyes underwent M-FLEK and 33 eyes underwent conventional PKP. Data on preoperative and postoperative manifest refraction, uncorrected visual acuity and best-corrected visual acuity (BCVA), endothelial cell counts, vector analysis, and complications were retrieved and analyzed. At 12 months of follow-up, the mean logMAR BCVA was 0.31 ± 0.55 in the M-FLEK group and 0.32 ± 0.21 in the PKP group (P = 0.91). The mean spherical equivalent was similar between the groups. The mean manifest cylinder was significantly lower in the M-FLEK group (-2.84 ± 1.08 diopters) than in the PKP group (-3.93 ± 2.26 diopters; P = 0.03). There was a smaller mean endothelial cell loss in the M-FLEK group compared with the PKP group (32.1% vs 38.7%, respectively, P = 0.17) 1 year postoperatively. The complication rates were similar for both groups. M-FLEK appears to be a safe procedure that results in less astigmatism and a trend toward higher endothelial cell counts compared with conventional PKP, with similar postoperative BCVA.Cornea 03/2014; 33(5). DOI:10.1097/ICO.0000000000000080 · 2.04 Impact Factor
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