Article

Viral Hepatitis Infections in Chronic Kidney Disease Patients and Renal Transplant Recipients.

Department of Internal Medicine, First Medical Faculty, Charles University, and Central Military Hospital Prague, Prague, Czech Republic.
Kidney and Blood Pressure Research (impact factor: 1.46). 06/2012; 35(6):454-467. DOI:10.1159/000338309 pp.454-467
Source: PubMed

ABSTRACT Within the last few decades, the incidence and prevalence of both hepatitis B and C infections have decreased among kidney disease patients. Significant advances have been made in the prevention of hepatitis B and C virus transmission in these high-risk populations; however, the transmission risk is still not negligible. Viral hepatitis infections represent a significant problem among kidney disease patients; patients on regular dialysis, as well as renal transplant recipients (RTRs) due to their epidemiological, virological, and clinical features. Chronic hepatitis B and C have a strong impact on the clinical course of kidney disease as well as on the clinical course after kidney transplantation. The purpose of this review is to focus on the epidemiology, transmission modes, natural courses, and treatment options of hepatitis B and C infections in both chronic kidney disease patients and RTRs.

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Keywords

Chronic hepatitis B
 
chronic kidney disease patients
 
clinical course
 
clinical features
 
decades
 
epidemiological
 
epidemiology
 
hepatitis B
 
high-risk populations
 
kidney disease
 
kidney disease patients
 
kidney transplantation
 
last
 
natural courses
 
regular dialysis
 
renal transplant recipients
 
Significant advances
 
significant problem
 
strong impact
 
treatment options
 

Petr Urbánek