Revisiting Regression in Autism: Heller's Dementia Infantilis Includes A Translation of Uber Dementia Infantilis

Yale Child Study Center, New Haven, CT, 06519, USA, .
Journal of Autism and Developmental Disorders (Impact Factor: 3.06). 06/2012; 43(2). DOI: 10.1007/s10803-012-1559-z
Source: PubMed


Theodor Heller first described a severe regression of adaptive function in normally developing children, something he termed dementia infantilis, over one 100 years ago. Dementia infantilis is most closely related to the modern diagnosis, childhood disintegrative disorder. We translate Heller's paper, Über Dementia Infantilis, and discuss similarities in presentation between Heller's cases, and a group of children with childhood disintegrative disorder. In particular we discuss a prodromal period of affective dysregulation described by Heller, and also evident in our sample, but not previously described in any detail since the publication of Über Dementia Infantilis.

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