Article

New approach to detecting counterfeit drugs in tablets by DART mass spectrometry

Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, 125315 Russia; Tokyo Boeki (Moscow Office), Moscow, Russia
Pharmaceutical Chemistry Journal (impact factor: 0.37). 05/2012; 45(5):306-308. DOI:10.1007/s11094-011-0622-y pp.306-308

ABSTRACT The possibility of using DART mass spectrometry for the identification of active ingredients in tableted drugs has been studied.
Analytical results for some drugs such as glycin, nootropyl, anaprilin, mexidol, and biseptol are presented. The benefits
and limitations of DART mass spectrometry as applied to fast screening of tableted pharmaceuticals for detecting counterfeits
are discussed.

Key wordsDART mass spectrometry–fast screening of pharmaceuticals for counterfeits

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Keywords

active ingredients
 
Analytical results
 
anaprilin
 
DART mass spectrometry
 
detecting counterfeits
 
fast screening
 
glycin
 
Key wordsDART mass spectrometry–fast screening
 
limitations
 
mexidol
 
tableted drugs
 
tableted pharmaceuticals