Article

The role of mercury in the processes of vital activity of the human and mammalian organisms

Russian Journal of General Chemistry (impact factor: 0.47). 04/2012; 80(13):2694-2703. DOI:10.1134/S1070363210130037 pp.2694-2703

ABSTRACT Mercury belongs to one of the most common heavy metals that have high biological activity in relation to human and animal
cells. However, the physiological role of mercury in the metabolism of eukaryotic cells is still unclear. The given review
provides current information on certain properties of mercury, the mechanisms of penetration of Hg (II) inside cells, its
genotoxic and cytotoxic effects, as well as the role of mercury in the induction of autoimmune processes involving production
of autoantibodies to the nucleolar protein fibrillarin.

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Keywords

autoimmune processes
 
biological activity
 
certain properties
 
common heavy metals
 
current information
 
eukaryotic cells
 
given review
 
Hg
 
metabolism
 
nucleolar protein fibrillarin
 
penetration
 
physiological role