Association of tobacco use and periapical pathosis - a systematic review
ABSTRACT Walter C, Rodriguez FR, Taner B, Hecker H, Weiger R. Association of tobacco use and periapical pathosis - a systematic review. International Endodontic Journal. ABSTRACT: The aim was to review the current evidence regarding an association between tobacco use, that is, cigarette smoking, and periapical pathosis. A systematic MEDLINE search of articles published prior to October 2011 (4th) was conducted using the keywords 'smoking and endodontics OR smoking and periapical index'. The study selection, data preparation and validity assessment were conducted by two reviewers. Nine studies fulfilled the inclusion criteria and represented data from 3008 individuals. The studies differed with respect to (i) study design, (ii) radiographic techniques, (iii) assessment of periapical pathosis, (iv) classification of smoking characteristics and/or (v) potential confounders accounted for in the analyses. Five of six cross-sectional studies revealed a significant positive association (OR 1.35-16.8) between periapical pathosis and current cigarette smoking. One of three longitudinal studies indicated an increased risk (OR 1.7) of root treated teeth for current smokers. The substantial heterogeneity of the included studies limited their interpretation. Further, well-designed studies are required to investigate the association between tobacco use and periapical pathosis.
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ABSTRACT: Effects of smoking cessation on the outcomes of non-surgical periodontal therapy: a systematic review and individual patient data meta-analysis. Chambrone L, Preshaw PM, Rosa EF, Heasman PA, Romito GA, Pannuti CM, Tu YK. J Clin Periodontol 2013;40:607-15. Clemens Walter, DMD, Anton Friedmann, DMD, PhD PURPOSE/QUESTION: "Does quitting smoking improve the clinical outcome of non-surgical periodontal treatment?" The study was self-funded by the authors Systematic review with individual patient data meta-analysis Level 2: Systematic review/meta-analysis of disease-oriented outcomes from two prospective cohort studies STRENGTH OF THE RECOMMENDATION GRADE: Level B: consistent findings from two good-quality prospective cohort studies and systematic review/meta-analysis of disease-oriented outcomes.The journal of evidence-based dental practice 12/2013; 13(4):142-4. DOI:10.1016/j.jebdp.2013.10.001
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ABSTRACT: Background The treatment of periodontal-endodontic lesions is challenging due to the involvement of both periodontal and endodontic tissues.Objective To evaluate the treatment options and outcomes of periodontal-endodontic lesions.Material and methodsA systematic literature search was performed for articles published by 12 May 2013 using electronic databases and hand search. Two reviewers conducted the study selection, data collection and validity assessment. The PRISMA criteria were applied. From 1087 titles identified by the search strategy, five studies and 18 case reports were included.ResultsClinical studies and case reports were published from the years 1981 to 2012. A pronounced heterogeneity exists among studies regarding applied treatment protocols and quality of reporting. In all clinical studies, comprising 111 teeth, a non-surgical root canal treatment (RCT) was performed as initial treatment step. Non-surgical and/or a surgical periodontal therapy was applied in some studies without reevaluation of the endodontic healing. Probing pocket depth reductions were reported in all included studies, comprising the data from 74 teeth at follow-up.ConclusionsA sequential treatment with root canal treatment as a first treatment step appears to be reasonable. An adequate time for tissue healing is suggested prior to reevaluation.This article is protected by copyright. All rights reserved.Journal Of Clinical Periodontology 04/2014; 41(8). DOI:10.1111/jcpe.12265 · 3.61 Impact Factor
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ABSTRACT: Background: The Calcium Hydroxide has been widely used as an intracanal dressing and in combination with restorative and endodontic materials and its main goal is the tissue reparation. However, when the patient has chronic stress, the immunological response and tissue repair decreases in both the epithelial and connective tissue. Therefore, the aim was to analyze the effect of chronic stress on the tissue response in rats exposed to calcium hydroxide (CH). Materials and Methods: A total of 60 wistar rats were anesthetized, and a polyethylene tube containing CH was inserted under the skin. After 24 h, they were divided into two groups: Calcium hydroxide + stress (CHSG) n = 30 and calcium hydroxide (CHG) n = 30. They were stressed by physical restraint, for 12 h each day for periods of 7, 15 and 30 days when 10 animals from each group were euthanized. The tissues surrounding the polyethylene tubes were removed, and slides were prepared and stained with hematoxylin and eosin. The analysis was performed with an optical microscope with magnification of 4-400 times by a blinded senior examiner. The sample slides were classified according to the following scores 0 - absent/1 - present/2 - infiltrate to: Inflammatory infiltrate containing fibrous condensation, lymphocytes, plasmacytes, macrophages, neutrophils, and eosinophils. The data were statistically analyzed using the Student’s t-test (P < 0.05) for paired samples. Results: The exposure time of 7 days elicited no statistical difference between groups (P > 0.05). The 15 days exposure group had higher averages for CHG to eosinophils and inflammatory infiltrate (P < 0.05). In 30 days, CHG showed higher averages to inflammatory infiltrate and lower averages to FC (P < 0.05). Conclusions: Some modified patterns of responses in the CHSG were observed at 15 days and 30 days.07/2014; 6(4):4-8.