Article

[The thousand and one facets of skin stem cells. The future has found new roots].

Service de Dermatopathologie, CHU de Liège.
Revue médicale de Liège 03/2012; 67(3):143-6. pp.143-6
Source: PubMed

ABSTRACT Multipotent stem cells of adult skin are found in distinct biological locations identified as niches. These stem cell populations are defined by specific molecular and functional attributes. The epidermal stem cells are found in the interfollicular areas and in the bulge and isthmus of the hair follicles. Dermal stem cells are harbored in the peripilar connective tissue sheaths and in the hair papilla. Some skin stem cells are found in extracutaneous sites. Other stem cells are involved in pathology, such as neoplastic stem cells identified in malignant melanomas.

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Keywords

adult skin
 
bulge
 
distinct biological locations
 
functional attributes
 
hair follicles
 
hair papilla
 
interfollicular areas
 
malignant melanomas
 
pathology
 
peripilar connective tissue sheaths
 
specific molecular
 
stem cell populations
 
stem cells
 

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