Influence of nanomaterials on stem cell differentiation: Designing an appropriate nanobiointerface

Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
International Journal of Nanomedicine (Impact Factor: 4.38). 04/2012; 7:2211-25. DOI: 10.2147/IJN.S29975
Source: PubMed

ABSTRACT During the last decade, due to advances in functionalization chemistry, novel nanobiomaterials with applications in tissue engineering and regenerative medicine have been developed. These novel materials with their unique physical and chemical properties are bioactive hierarchical structures that hold great promise for future development of human tissues. Thus, various nanomaterials are currently being intensively explored in the directed differentiation of stem cells, the design of novel bioactive scaffolds, and new research avenues towards tissue regeneration. This paper illustrates the latest achievements in the applications of nanotechnology in tissue engineering in the field of regenerative medicine.

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Available from: Razvan Ilie, Sep 26, 2015
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    • "During the last decade, CNTs have shown evidence of their electrical conductive capacity, strong mechanical properties and morphological similarity to neurites [17] leading to the advancements for tissue engineering and regenerative medicine using CNT based stem cells for tissue repair. CNTs have unique advantages in controlling stem cell function and in tissue regeneration [18] due to their biomimetic characteristics and special biological and mechanical properties [19]. In the past, stem cell therapy seemed like it may present a cure for all medical ailments, but problems such as immune system clearance, control of differentiation in the body, etc have hindered progress. "
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