Article

Stroke and renal dysfunction: are we always conscious of this relationship?

Clinica Medica, Department of Clinical and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Clinical and Applied Thrombosis/Hemostasis (impact factor: 1.33). 06/2012; 18(3):305-11. DOI:10.1177/1076029611423388 pp.305-11
Source: PubMed

ABSTRACT Cerebrovascular disease may represent an important clinical presentation of atherosclerosis in chronic kidney disease (CKD), and atherosclerosis is frequently encountered in CKD. In fact, kidney disease is now considered a risk factor for development of cardiovascular disease. Although guidelines for primary prevention of stroke have been recently published, CKD is hardly mentioned. Based on a series of available studies, we analyzed the relationship between reduced renal function, end-stage renal disease (ESRD), and stroke. Reduced renal function and risk of stroke appear to be related to the highest risk of patients on dialysis treatment. Primary and secondary prevention of stroke should be encouraged in participants with renal dysfunction.

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Keywords

available studies
 
cardiovascular disease
 
Cerebrovascular disease
 
chronic kidney disease
 
clinical presentation
 
dialysis treatment
 
end-stage renal disease
 
highest risk
 
kidney disease
 
primary prevention
 
Reduced renal function
 
renal dysfunction
 
renal function
 
risk factor
 
secondary prevention