Dexmedetomidine in a Child with Methylphenidate Intoxication

Pediatric Intensive Care Unit, Section of Critical Care Medicine, Children's Hospital Colorado, 13123 East 17th Ave, Mail Stop 8414, Aurora, CO, 80045, USA, .
The Indian Journal of Pediatrics (Impact Factor: 0.87). 05/2012; 80(4). DOI: 10.1007/s12098-012-0757-1
Source: PubMed


Methylphenidate intoxication, due to accidental ingestion, is a common occurrence in pediatrics. Symptoms of extreme agitation are typically controlled with benzodiazepines or barbiturates. There is, however, a legitimate risk of mechanical ventilation due to respiratory depression with increasing doses of benzodiazepines. The authors describe a case of 7-y-old girl with methylphenidate toxicity where dexmedetomidine was successfully used to manage agitation and cardiovascular stimulation without respiratory compromise.

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