The Increasing Frequency of Mania and Bipolar Disorder

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
The Journal of nervous and mental disease (Impact Factor: 1.69). 05/2012; 200(5):380-7. DOI: 10.1097/NMD.0b013e3182531f17
Source: PubMed


The frequency of mania has not changed during the last century even with the development of new diagnostic criteria sets. More specifically, from the mid-1970s to 2000, the rate of mania (variably labeled major affective disorder-bipolar disorder and bipolar I disorder) was consistently identified in US and international studies as ranging from 0.4% to 1.6%. By the late 1990s to the 2000s, the prevalence reported by some researchers for bipolar disorders (I and II and others) was in the 5% to 7% and higher ranges. The purpose of this paper was to review explanations for this change and the potentially negative impacts on the field.

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