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The Peaceful Mind Program: A Pilot Test of a Cognitive-Behavioral Therapy-Based Intervention for Anxious Patients With Dementia.

From VA HSR&D Houston Center of Excellence (MAS, JC, ALB, NW, NJP, MEK), Michael E. DeBakey VA Medical Center (MAS, CK-S, NJP, MEK), and Baylor College of Medicine (MAS, JC, ALB, NW, NJP, SPW, MEK), Houston, TX; VA South Central Mental Illness Research, Education and Clinical Center, Washington, DC (MAS, ALS, MEK); Center for Mental Health and Aging, The University of Alabama, Tuscaloosa (ALS); Research and Development Service, Tuscaloosa VA Medical Center, Tuscaloosa (ALS); Puget Sound VA Medical Center, Seattle, WA (ALP); Wake Forest School of Medicine, Winston-Salem, NC (GAB); and The University of Texas Health Science Center at Houston, The Mischer Neuroscience Institute and Memorial Hermann Hospital, Houston, TX (PES).
The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry (Impact Factor: 3.35). 04/2012; DOI: 10.1097/JGP.0b013e318252e5b5
Source: PubMed

ABSTRACT OBJECTIVES:: To assess feasibility and to conduct a preliminary evaluation of outcomes following Peaceful Mind, a cognitive-behavioral therapy-based intervention for anxiety in dementia, relative to usual care. DESIGN:: Pilot randomized controlled trial including assessments at baseline and 3 and 6 months. SETTING:: Houston, TX. PARTICIPANTS:: Thirty-two outpatients diagnosed with mild (47%) or moderate (53%) dementia receiving care through outpatient clinics at the Veterans Affairs medical center, Baylor College of Medicine, Harris County Hospital District, and community day centers for dementia, and their collaterals, who spent at least 8 hours a week with them. INTERVENTION:: Peaceful Mind included up to 12 weekly in-home sessions (mean: 8.7, SD: 2.27) during the initial 3 months and up to eight brief telephone sessions (mean: 5.4, SD: 3.17) during months 3-6, involving self-monitoring for anxiety, deep breathing, and optional skills (coping self-statements, behavioral activation, and sleep management). Patients learned skills, and collaterals served as coaches. In usual care, patients received diagnostic feedback, and providers were informed of inclusion status. MEASUREMENTS:: Neuropsychiatric Inventory-Anxiety subscale, Rating Anxiety in Dementia scale, Penn State Worry Questionnaire-Abbreviated, Geriatric Anxiety Inventory, Geriatric Depression Scale, Quality of Life in Alzheimer disease, Patient Health Questionnaire, and Client Satisfaction Questionnaire. RESULTS:: Feasibility was demonstrated with regard to recruitment, attrition, and treatment characteristics. At 3 months, clinicians rated patients receiving Peaceful Mind as less anxious, and patients rated themselves as having higher quality of life; collaterals reported less distress related to loved ones' anxiety. Although significant positive effects were not noted in other outcomes or at 6-month follow-up, the pilot nature of the trial prohibits conclusions about efficacy. CONCLUSIONS:: Results support that Peaceful Mind is ready for future comparative clinical trials.

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    ABSTRACT: We compared the psychometric performance of two validated self-report anxiety symptom measures when rated by people with dementia versus collaterals (as proxies). Forty-one participants with mild-to-moderate dementia and their respective collaterals completed the Geriatric Anxiety Inventory, the Penn State Worry Questionnaire-Abbreviated, and a structured diagnostic interview. We used descriptive and nonparametric statistics to compare scores according to respondent characteristics. Receiver operating characteristic (ROC) curves were calculated to establish the predictive validity of each instrument by rater type against a clinical diagnosis of an anxiety disorder. Participant and collateral ratings performed comparably for both instruments. However, collaterals tended to give more severe symptom ratings, and the best-performing cut-off scores were higher for collaterals. Our findings suggest that people with mild-to-moderate dementia can give reliable self-reports of anxiety symptoms, with validity comparable to reports obtained from collaterals. Scores obtained from multiple informants should be interpreted in context.
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