Gallbladder agenesis, a rare congenital disorder
ABSTRACT A 51-year-old woman presented with right upper abdominal discomfort for three weeks. Her medical history revealed a lower abdominal gynecological laparoscopy and an ileocaecal resection 7 years ago.
Blood samples including liver enzymes were within normal limits. An upper abdominal ultrasound failed to reveal a gallbladder. An MRI with MR-cholangiography confirmed the abscence of a gallbladder, thus the diagnosis of a gallbladder agenesis.
The patient was informed about the benign nature of her diagnosis and was discharged. The right upper abdominal discomfort was mild and untypical, and most probably not caused by the gallbladder agenesis.
Gallbladder agenesis is rare. The congenital disorder has to be taken into account if no gallbladder can be found during imaging or surgery. Sonography is not the adequate method for diagnosing gallbladder agenesis.
Article: Agenesis of the gallbladder.[Show abstract] [Hide abstract]
ABSTRACT: All case reports of agenesis of the gallbladder in our review of the literature have been categorized as to proved, probable, possible (insufficient evidence), or questionable on the basis of the amount and type of evidence available to support each claim. Thirty-seven authors have reported fifty-six patients in the English literature with proved agenesis of the gallbladder; agenesis was confirmed at operation in thirteen of these patients and at autopsy in forty-three. Three new cases of agenesis of the gallbladder are reported, two of which were confirmed at operation and one at autopsy.The American Journal of Surgery 01/1968; 114(6):917-26. DOI:10.1016/0002-9610(67)90418-7 · 2.41 Impact Factor
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ABSTRACT: The "WES" triad -- that is, the demonstration of the gallbladder Wall, the Echo of the stone, and the acoustic Shadow -- permits the specific diagnosis of stones in a contracted gallbladder. This triad positively identifies the gallbladder and helps to differentiate the contracted gallbladder with stones from a loop of bowel containing gas.Gastrointestinal Radiology 02/1981; 6(1):39-41. DOI:10.1007/BF01890219
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ABSTRACT: Agenesis of the gallbladder is a rare congenital anomaly occurring in 13 to 65 people of a population of 100,000. The rarity of the condition, combined with clinical and radiologic features that are indistinguishable from those of more common biliary conditions, means that it is rarely diagnosed preoperatively, and patients undergo unnecessary operative intervention. This case report describes the case of a 79-year-old symptomatic Caucasian man who underwent laparoscopic cholecystectomy for suspected choledocholithiasis despite imaging studies raising suspicion of gallbladder agenesis. Intra-operatively, the diagnosis of gallbladder agenesis and associated common bile duct stones was made. The preoperative diagnosis of this rare condition is difficult to make. However, with advances in biliary tract imaging and with heightened awareness of this anomaly, fewer patients will need to undergo unnecessary operative intervention. The authors review the different imaging modalities available to help diagnose this condition and highlight the importance of being aware of this rare anomaly to avoid an operation that carries a high risk of iatrogenic injury.Journal of Medical Case Reports 08/2010; 4:285. DOI:10.1186/1752-1947-4-285