Article

Malignant melanoma in transplant patients: a case report and review of the literature.

University of Notre Dame, Indiana, USA.
Cutis; cutaneous medicine for the practitioner (impact factor: 0.81). 03/2012; 89(3):133-6. pp.133-6
Source: PubMed

ABSTRACT The clinical course and outcome of malignant melanoma (MM) are well-established for immunocompetent groups; however, they are not well-documented for immunosuppressed populations. Specifically, the influence of immunosuppression may result in poorer outcomes, especially in more advanced cases of melanoma. We report a 67-year-old woman who had previously undergone a kidney and pancreas transplant and presented with American Joint Committee on Cancer (AJCC) stage IIIA melanoma with subsequent rapid demise. As medicine advances with greater numbers of organ transplant recipients, a multi-institutional prospective study for this at-risk population would be greatly beneficial to help characterize the incidence, progression, and prognosis of melanoma in posttransplant immunosuppressed populations.

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Keywords

67-year-old woman
 
American Joint Committee
 
clinical course
 
greater numbers
 
immunocompetent groups
 
malignant melanoma
 
organ transplant recipients
 
poorer outcomes
 
prognosis
 
subsequent rapid demise
 

A Nichole Sullivan