Prophylactic Use of Antipyretic Agents With Childhood Immunizations and Antibody Response: Reason for Concern?

University of Florida, Kissimmee, FL, USA.
Journal of Pediatric Health Care (Impact Factor: 1.44). 05/2012; 26(3):200-3. DOI: 10.1016/j.pedhc.2010.12.008
Source: PubMed


In the pediatric primary care setting, well-child visits constitute over 50% of all encounters, treating over 24 million children annually. Anticipatory guidance topics vary based on different ages, but immunizations are a focal point of all well-child visits. This article addresses the prophylactic use of antipyretic agents with the administration of immunizations as a potential reason of concern.
A literature review of the use of antipyretic agents in conjunction with immunizations and the effectiveness of treatment was performed.
Based on several studies, the standard recommendation of administering antipyretic agents with immunization administration was a routine. Twenty years later, the scientific evidence was questioned. A pivotal study questioned these standards, noting no benefit and potential decreased immune response.
Although the prophylactic use of antipyretics has been a standard in pediatrics, the lack of scientific support in the reduction of adverse effects of the vaccinations and the possibility of decreased immune response warrants further research.

14 Reads
  • [Show abstract] [Hide abstract]
    ABSTRACT: Theoretical frameworks developed in gerontological and recreational studies are useful reference points in the development of more comprehensive tourist behavior models. This paper attempts to provide a context for an understanding of vacation patterns of elderly Germans (FRG), which are described and analyzed within the contextual framework of an environmental motivational model. The influence of age and environmental factors on tourist participation is examined by comparisons of the behavior of four specified age groups. Modes of travel, destinations, length of vacation, accomodations, popularity of activities, and vacation memories, were all examined. Motivations inducing tourist travel were found to be similar across age cohorts. Spatial patterns are found to vary as the result of the interaction between the aging process and environmental forces. The elderly tended to seek less stressful modes of transportation and vacation habitats.
    Annals of Tourism Research 01/1989; 16(2):178–188. DOI:10.1016/0160-7383(89)90066-2 · 3.26 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Relationships between motivations for leisure and participation in types of activities and demographic and socioeconomic variables were studied in 1,089 elderly recreational vehicle tourists. Subjects were drawn from a popular winter recreational vehicle tourist area and data were gathered through a self-report survey instrument. Leisure motivations investigated were: rest and relaxation, association with friends and family, physical exercise, learning experience, and self-fulfillment. Chi-square analysis indicated significant relationships between motivations and selected active and sedentary leisure activities, age, occupation, income, and per ceived health status. Little relationship was ascertained between motivations and educational level.
    Journal of Travel Research 07/1980; 19(1):9-12. DOI:10.1177/004728758001900102 · 1.58 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The retired market approaches its travel purchases in two stages: preretirement planning and postretirement execution. This research examines the planning process, the changes that occur between it and the actual purchase, the reasons for these changes, and the several factors that should be considered in promoting travel services to this market in each stage.
    Journal of Travel Research 10/1980; 19(2):7-11. DOI:10.1177/004728758001900202 · 1.58 Impact Factor
Show more