Article

A case of endocrine mucin-producing sweat gland carcinoma

Department of Dermatology, University of Yamanashi, Yamanashi, Japan.
Pathology International (Impact Factor: 1.59). 05/2012; 62(5):344-6. DOI: 10.1111/j.1440-1827.2012.02793.x
Source: PubMed

ABSTRACT Endocrine mucin-producing sweat gland carcinoma (EMPSGC), which is an uncommon sweat gland tumor with a predilection for the eyelids, is morphologically analogous to solid papillary carcinoma of the breast. We report the case of a 55-year-old man with a subcutaneous tumor of the upper cheek. The pathological findings for this patient were compatible with those of reported cases of EMPSGC, and p63 staining revealed partial microinvasion into the dermis. On the basis of these findings, the patient was diagnosed with EMPSGC. It is reported that EMPSGC is a precursor of invasive mucinous carcinoma of the skin. Therefore, this patient was treated and followed up as if he had mucinous carcinoma of the skin. To the best of our knowledge, this is the first report of such a case from Japan.

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