Article

Lipoatrophic panniculitis of the ankles in childhood: differential diagnosis with subcutaneous panniculitis-like T-cell lymphoma.

Servicio de Anatomía Patológica, Capio Fundación Jiménez Díaz, Madrid, Spain.
The American Journal of dermatopathology (impact factor: 1.3). 05/2012; 34(3):295-300. DOI:10.1097/DAD.0b013e31822e68ca pp.295-300
Source: PubMed

ABSTRACT We describe the clinical, histopathologic, immunohistochemical, and molecular findings in an additional case of lipoatrophic panniculitis selectively involving the ankles in a 12-year-old boy. This idiopathic, rarely reported entity is presumed to have an autoimmune pathogenesis. Histological findings are a lipophagic lobular panniculits, that in our case featured focally increased numbers of lymphocytes rimming the adipocytes, and infiltration of vascular walls by mildly atypical lymphoid cells, raising the differential diagnosis of subcutaneous panniculitis-like T-cell lymphoma.

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Keywords

ankles
 
differential diagnosis
 
Histological findings
 
immunohistochemical
 
infiltration
 
lipoatrophic panniculitis
 
mildly atypical lymphoid cells
 
subcutaneous panniculitis-like T-cell lymphoma