Conference Paper

Cancer disease: integrative modelling approaches

Sch. of Math. Sci., Nottingham Univ.
DOI: 10.1109/ISBI.2006.1625040 Conference: Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on
Source: DBLP

ABSTRACT Cancer is a complex disease in which a variety of phenomena interact over a wide range of spatial and temporal scales. In this article a theoretical framework will be introduced that is capable of linking together such processes to produce a detailed model of vascular tumour growth. The model is formulated as a hybrid cellular automaton and contains submodels that describe subcellular, cellular and tissue level features. Model simulations will be presented to illustrate the effect that coupling between these different elements has on the tumour's evolution and its response to chemotherapy

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