Article

[Prevalence of sleep-disordered breathing in patients with retinal vein occlusion].

Department of Ophthalmology, Toho University Sakura Medical Center, Japan.
Nippon Ganka Gakkai zasshi 02/2012; 116(2):81-5. pp.81-5
Source: PubMed

ABSTRACT To investigate the prevalence of sleep-disordered breathing (SDB) in retinal vein occlusion (RVO) patients.
Forty RVO patients who had undergone either vitreous surgery or anti-coagulation therapy were included in this study. Pulse oximetry was conducted during the night and 4% oxygen desaturation index (4% ODI times/hour) and mean SpO2 (%) were calculated. If 4% ODI > or = 5, SDB was diagnosed. The results were compared between branch retinal vein occlusion (BRVO), and central retinal vein occlusion (CRVO). In addition, simple linear regression analyses were conducted to investigate whether 4% ODI related to systemic factors for RVO patients, i.e., incidences of hypertension and diabetes and body mass index(BMI kg/m2).
Forty two percent of the men, 33% of the women and 37% of all the RVO patients were diagnosed as having SDB. The prevalence of SDB and 4% ODI, and the mean SpO2 were not significantly different between the BRVO and CRVO cases. The incidences of diabetes tended to correlate to the 4% ODI, however, neither proved significant. The BMI had a statistic correlation with the 4% ODI.
The results of our study suggested that RVO cases have a high frequency of SDB. We believe that at the time of ophthalmic medical examinations or during the treatment of RVO, ophthalmologists should be aware of the possibility of SDB.

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Keywords

4% oxygen desaturation index
 
anti-coagulation therapy
 
body mass index(BMI kg/m2)
 
branch retinal vein occlusion
 
BRVO
 
central retinal vein occlusion
 
CRVO
 
CRVO cases
 
diabetes
 
mean SpO2
 
ophthalmic medical examinations
 
Pulse oximetry
 
retinal vein occlusion
 
RVO
 
RVO cases
 
RVO patients
 
SDB
 
simple linear regression analyses
 
statistic correlation
 
vitreous surgery