Article

A dual-modality probe utilizing intravascular ultrasound and optical coherence tomography for intravascular imaging applications

Dept. of Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control (impact factor: 1.69). 01/2011; DOI:10.1109/TUFFC.2010.1758 pp.2839 - 2843
Source: IEEE Xplore

ABSTRACT We have developed a dual-modality biomedical imaging probe utilizing intravascular ultrasound (IVUS) and optical coherence tomography (OCT). It consists of an OCT probe, a miniature ultrasonic transducer and a fixed mirror. The mirror was mounted at the head of the hybrid probe 45° relative to the light and the ultrasound beams to change their propagation directions. The probe was designed to be able to cover a larger area in blood vessel by IVUS and then visualize a specific point at a much finer image resolution using OCT. To demonstrate both its feasibility and potential clinical applications, we used this ultrasound-guide OCT probe to image a rabbit aorta in vitro. The results offer convincing evidence that the complementary natures of these two modalities may yield beneficial results that could not have otherwise been obtained.

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Keywords

dual-modality biomedical imaging probe utilizing intravascular ultrasound
 
feasibility
 
finer image resolution
 
hybrid probe 45°
 
larger area
 
miniature ultrasonic transducer
 
OCT
 
OCT probe
 
potential clinical applications
 
rabbit aorta
 
results offer convincing evidence
 
specific point
 
two modalities
 
ultrasound-guide OCT probe
 
vitro
 

Hao-Chung Yang