Total hip replacement for the treatment of acute femoral neck fractures: results from the National Joint Registry of England and Wales at 3-5 years after surgery
ABSTRACT This paper describes, for the first time, the outcomes of patients undergoing total hip replacement for acute fractured neck of femur (#NOF) as recorded by the National Joint Registry of England and Wales (NJR).
In the NJR we identified 1,302 of 157,232 Hospital Episode Statistics linked patients who had been recorded as having a total hip replacement for acute #NOF between April 2003 and November 2008.
The revision rate at five years for fully uncemented components was 4.1% (95% confidence interval [CI]: 2.2-7.3%), for hybrid it was 2.2% (95% CI: 0.9%-5.3%) and for fully cemented components 0.9% (95% CI: 0.4-2.0%). Five-year revision rates were increased for those whose operations were performed via a posterior versus a lateral approach. The Kaplan-Meier estimate of 30-day mortality was 1.4% (95% CI: 1.0-2.4%), which is over double the 30-day mortality rate for total hip replacement identified by the Office for National Statistics. The mean length of stay was also increased for those undergoing total hip replacements for #NOF compared with non-emergency indications.
Our data suggest that total hip replacements for acute #NOF give comparable results with total hip replacements for other indications.
- Injury 07/2012; 43(10):1621-2. DOI:10.1016/j.injury.2012.07.189 · 2.46 Impact Factor
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ABSTRACT: United Kingdom National Institute for Health and Clinical Excellence guidelines recommend the use of total hip replacement (THR) for displaced intracapsular fractures of the femoral neck in cognitively intact patients, who were independently mobile prior to the injury. This study aimed to analyse the risk factors associated with revision of the implant and mortality following THR, and to quantify risk. National Joint Registry data recording a THR performed for acute fracture of the femoral neck between 2003 and 2010 were analysed. Cox proportional hazards models were used to investigate the extent to which risk of revision was related to specific covariates. Multivariable logistic regression was used to analyse factors affecting peri-operative mortality (< 90 days). A total of 4323 procedures were studied. There were 80 patients who had undergone revision surgery at the time of censoring (five-year revision rate 3.25%, 95% confidence interval 2.44 to 4.07) and 137 patients (3.2%) patients died within 90 days. After adjusting for patient and surgeon characteristics, an increased risk of revision was associated with the use of cementless prostheses compared with cemented (hazard ratio (HR) 1.33, p = 0.021). Revision was independent of bearing surface and head size. The risk of mortality within 90 days was significantly increased with higher American Society of Anesthesiologists (ASA) grade (grade 3: odds ratio (OR) 4.04, p < 0.001; grade 4/5: OR 20.26, p < 0.001; both compared with grades 1/2) and older age (≥ 75 years: OR 1.65, p = 0.025), but reduced over the study period (9% relative risk reduction per year). THR is a good option in patients aged < 75 years and with ASA 1/2. Cementation of the femoral component does not adversely affect peri-operative mortality but improves survival of the implant in the mid-term when compared with cementless femoral components. There are no benefits of using head sizes > 28 mm or bearings other than metal-on-polyethylene. More research is required to determine the benefits of THR over hemiarthroplasty in older patients and those with ASA grades > 2.The Bone & Joint Journal 11/2012; 94(11):1557-66. DOI:10.1302/0301-620X.94B11.29689 · 2.80 Impact Factor
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ABSTRACT: Charnley and Stanmore cemented femoral stems are of the most studied stems and in vivo long-term results up to 15 and 20 years, respectively, have been published. The in vitro study hereby described correlates biomechanical factors such as stem position in the femoral canal, cement thickness and fatigue cracks with in vivo published results. Four of each femoral stems were loaded and tested in fatigue simulating stair climbing during one million cycles at 2 Hz. After the fatigue experiments all implanted femurs were sectioned and analyzed. Correlation between in vivo long-term published results with debonding and cracking was performed. Finite element models of the Stanmore and Charnley stems were used to predict tensile and compression stresses in the cement mantle to detect the critical regions and correlate these with experimental results. Within the analysis of the sections we observed some defects relatively to the positioning of the stems. The Stanmore stem was mainly placed in a valgus position while the Charnley stem was in a varus position. The number of cracks in the stem–cement interface was more visible for the Charnley stems. The lateral aspect was the most critical since more cracks were visible. Cement damage was more pronounced proximally and especially where cancellous bone presents higher thickness. The stems presented different behaviors in the cement–bone interface. The finite element results showed agreement between the maximum principal stresses and the regions of more cracks. The in vitro results are comparable with long-term in vivo published results. The experimental study hereby described can be used as a pre-clinical test to predict the performance of new implants before being launched into the market.International Journal of Damage Mechanics 07/2013; 22(5):719-736. DOI:10.1177/1056789512462426 · 1.72 Impact Factor