Efficacy of aphrodisiac plants towards improvement in semen quality and motility in infertile males
Infertility is the inability to conceive after one year of unprotected intercourse. In the present study, herbal composition prepared by using medicinal plants having aphrodisiac potentials was administered orally to the albino rats for 40 days and to the oligospermic patients for 90 days in order to prove the efficacy of herbal composition. Herbal composition was the mixture (powder form) of the medicinal plants namely, Mucuna pruriens (Linn), Chlorophytum borivillianum (Sant and Fernand), and Eulophia campestris (Wall). In the neem oil treated albino rats, there was significant reduction in almost all the parameters viz. body weight, testes and epididymes weight, sperm density and motility, serum levels of testosterone, FSH, and LH compared with control rats. Treatment with said herbal composition for 40 days results significant increased in the body weight, testis, and epididymes weight in rats. Concomitantly the sperm motility and the sperm density were significantly increased. After 90 days of treatment with this herbal composition, sperm density vis-a-vis motility was increased in oligozoospermic patients as a result of elevation in serum testosterone levels. No side effects were noticed during the entire duration of the trial.
Available from: Bhaskar Gupta
Journal of medicinal plant research 08/2012; 6(33):4825-4831. DOI:10.5897/JMPR12.916 · 0.88 Impact Factor
Available from: Zakia Khanam
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ABSTRACT: Safed musli (Chlorophytum borivilianum) is an eminent medicinal plant of India and considered as a 'white gold' or 'divya aushad' in Indian systems of medicine. In Ayurveda, C. borivilianum belongs to the group of "Vajikaran Rasayana' corroborated to its rejuvenating, aphrodisiac, natural sex tonic properties and effective in alleviating sexual disorders. It is largely used as ethnic medicine by local healers of indigenous communities of India.
A thorough bibliographic investigation was carried out by analyzing worldwide accepted scientific data base (Pub Med, SciFinder, Scopus and Web of Science), thesis, recognized books, non impact and non indexed journals.
Traditionally, C. borivilianum is well known for treating male impotency in India. The multi therapeutic and nutritional importance of C. borivilianum is attributed to the rich source of phytochemicals particularly saponins. Recently, C. borivilianum has gained well established domestic (Indian) and international market for being herbal alternative of "Viagra" without any side effects. Under the trade name 'Nai Chetna', the state government of Gujrat, India, has launched a novel potency drug from C. borivilianum. Modern pharmacological studies of C. borivilianum have demonstrated a wide range of pharmacological activities, most importantly aphrodisiac, immunomodulatory and anticancer activities.
The increased commercial exploitation of C. borivilianum and low productivity of this endangered plant has raised the concern over its conservation. It has been envisaged that efforts should be made to standardize, encourage and popularize the cultivation of C. borivilianum as a commercial crop. The analysis of previous pharmacological investigations suggested lack of substantial scientific evidences in various studies and do not stand the test of critical assessment. Due to high economic value, C. borivilianum has also encountered a problem of adulteration with closely resembling medicinally inferior species. The studies available on toxicity, safety and quality of C. borivilianum are inadequate for providing information on commercial utilization. Thus, the present review summarizes comprehensive information on C. borivilianum and possible scope for future research to fill the existing lacunae on its different aspects of the study.
Journal of ethnopharmacology 09/2013; 150(2). DOI:10.1016/j.jep.2013.08.064 · 3.00 Impact Factor
Available from: Ademola Oremosu
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ABSTRACT: Aims: To determine the effect of oral administration of methanolic seed extract of Mucuna pruriens (M. pruriens) on oestrous cycle, ovulation, reproductive hormones and oxidative stress in the ovary of cyclic Sprague-Dawley rats. Methodology: Forty female Sprague-Dawley rats with regular 4 days cycle averagely weighing 145 g were used. Methanolic extract of M. pruriens was given orally at 50, 100 and 200 mg/kg body weight. Oestrous cycle was monitored daily. At the end of the experiment animals were sacrificed by cervical dislocation. Oocytes were counted, blood and ovaries were assayed for hormonal and biochemical studies respectively. Results: Oestrous cycle remained unchanged in the treatment groups. Catalase and superoxide dismutase levels were increased slightly compared to control. A dose dependent increase in FSH and LH (p < 0.05 at 200 mg/kg) levels were observed with an 3149 increase in the number of oocytes released at ovulation compared to control. Conclusion: M. pruriens seed extract has the potential to enhance fertility by increasing serum levels of FSH and LH which in turn increases the number of oocytes released at ovulation possibly through its antioxidant properties.
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