Correction to Significance of Xenobiotic Metabolism for Bioaccumulation Kinetics of Organic Chemicals in Gammarus pulex.

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Correction to Significance of Xenobiotic Metabolism for
Bioaccumulation Kinetics of Organic Chemicals in Gammarus pulex
Roman Ashauer,* Anita Hintermeister, Isabel O’Connor, Maline Elumelu, Juliane Hollender,
and Beate I. Escher
Environ. Sci. Technol. 2012, 46 (6), 3498−3508. DOI: 10.1021/es204611h.
*
S Supporting Information
The authors regret that in our article1the data for
2,4-dichlorophenol (CAS 120-83-2) need to be corrected.
In Table 1 the corrected BAF of 2,4-dichlorophenol is 38
L/kgwet weight, the corrected MEFM1(2,4-dichlorophenol-sulfate)
is 1935 L/kgwet weight, and the corrected MEFM2 is 129
L/kgwet weight. In Table 2 the corrected model parameters (with
95% confidence intervals) for 2,4-dichlorophenol are 6815
(0; 62871) L × kg−1× d−1for kin_parent, 156 (0; 1594) d−1for
kout_parent, 21.27 (0; 48.6) d−1for kmet1, 0.415 (0.34; 0.49) d−1
for kloss_met1, 3.627 (0; 9.8) d−1for kmet2, and 1.063 (0; 2.69) for
kloss_met2.
The Supporting Information is also updated with the
corrected raw data for the biotransformation modeling and
Figure 1 shows the corrected time course of bioaccumulation,
biotransformation, and elimination kinetics for 2,4-dichlorophe-
nol and its metabolites (top part of Figure 3 in original article).
The corrected values do not change any conclusion in our article
because the relation of BAF to MEFs for 2,4-dichlorophenol did not
change and the compound had been excluded from the comparison
with the study based on total14C measurements. Note however,
that the corrected BAF and MEF values for 2,4-dichlorophenol are
higher than those originally published.
■ASSOCIATED CONTENT
*
Updated with the corrected raw data for the biotransformation
modeling. This material is available free of charge via the
Internet at http://pubs.acs.org.
S Supporting Information
Published: March 29, 2012
Figure 1. Molecular structures, label positions, exposure concentration (left), bioaccumulation, biotransformation, and elimination kinetics (right,
transfer to fresh media indicated by dashed line), and model structure (middle) for 2,4-dichlorophenol.
■REFERENCES
(1) Ashauer, R.; Hintermeister, A.; O’Connor, I.; Elumelu, M.;
Hollender, J.; Escher, B. I. Significance of Xenobiotic Metabolism for
Bioaccumulation Kinetics of Organic Chemicals in Gammarus pulex.
Environ. Sci. Technol. 2012, 46 (6), 3498−3508.
Addition/Correction
pubs.acs.org/est
© 2012 American Chemical Society
4682
dx.doi.org/10.1021/es301072j | Environ. Sci. Technol. 2012, 46, 4682−4682